‘Supercentenarian’ or ‘Super centuries old’, ie people who have succeeded in turning 110, offer more useful information in lifetime studies than those who are over 100 (Centenarian). The reason for the difference is not only that Supercentenarians live longer than Centenarian; better combat age-related chronic diseases. According to the news in Tech Explorist, Supercentenarian; They can be resistant to cancer affecting Alzheimer’s, heart disease and even Centenarian, but it is not clear why some people entered this ‘elite’ group and others did not. The mystery of supercentenarian can be solved: In a recent study, scientists first reprogrammed a 114 year old woman’s cells in stimulated Pluripotent Stem Cells (iPSCs). The study will allow scientists to unravel the mystery over why Supercentenarian lives a longer and healthier life. Scientists; He reprogrammed the blood cells from the 114-year-old woman we mentioned above, a 43-year-old healthy individual, and an 8-year-old child with premature aging disease (progeria) in iPSCs. The researchers then transformed these cells into mesenchymal stem cells. Mesenchymal stem cells are cell types that help protect and repair the structural tissues of the body. As a result of the study, Supercentenarian cells; It was observed that it had a faster transformation than healthy cell and progeria samples. In addition, as expected, telomeres with a protective DNA cap and shrinking as we get older were also renewed. A technological obstacle has been overcome with this research, and studies can be started for different cells through similar sample groups.
